Recombinant human BMP-11/GDF-11 protein
GDF11 also known as growth/differentiation factor 11. The protein secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. These play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Recombinant human GDF11, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Growth/differentiation factor 11, BMP-11, BMP11, Bone morphogenetic protein 11
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
14.8 kDa (132aa)
Additionnal Information
References & Citations
Gamer L.W., et al. (1999) Dev. Biol. 208:222-232
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_005802
Uniprot Accession Number
O95390
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSNLGLDCD EHSSESRCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGQC EYMFMQKYPH THLVQQANPR GSAGPCCTPT KMSPINMLYF NDKQQIIYGK IPGMVVDRCG CS
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