Recombinant human MINCLE/CLEC4E protein

CLEC4E also known as C-type lectin domain family 4, member E. CLEC4E is a C-type lectin receptor expressed by a variety of antigen presenting cells including macrophages, neutrophils, dendritic cells and B cells; a variety of stimuli including stress are known to induce the expression of CLEC4E. Recombinant human CLEC4E, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

CLEC4E, CLECSF9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, Macrophage lectin 2, Macrophage-inducible C-type lectin, MINCLE, NtmntanCLEC4E Ege lectin 2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

22.9 kDa (200aa)

Additionnal Information

CLEC 4E, CLEC4E, CLECSF9, C-type lectin domain family 4, member E, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, Macrophage lectin 2, Macrophage-inducible C-type lectin, MINCLE, NtmntanCLEC4E Ege lectin 2, ATGP3025-10 µg, ATGP3025-20 µg, ATGP3025-50 µg, ATGP3025-100 µg, ATGP3025-250 µg, ATGP3025-500 µg, ATGP3025-1 mg, ATGP3025-010, ATGP3025-020, ATGP3025-050, ATGP3025-100, ATGP3025-250, ATGP3025-500, ATGP3025-01M

References & Citations

Furukawa A., et al. (2013) Proc. Natl. Acad. Sci. u.S.A. 110 (43), 17438-17443; ; Kawata K., et al. (2012) J. Autoimmun. 39 (4), 315-322;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_055173

Uniprot Accession Number

Q9ULY5

Species

Human

AA Sequence

RCVVTFRIF QTCDEKKFQL PENFTELSCY NYGSGSVKNC CPLNWEYFQS SCYFFSTDTI SWALSLKNCS AMGAHLVVIN SQEEQEFLSY KKPKMREFFI GLSDQVVEGQ WQWVDGTPLT KSLSFWDVGE PNNIATLEDC ATMRDSSNPR QNWNDVTCFL NYFRICEMVG INPLNKGKSL