Recombinant human SUOX protein

SuOX also known as sulfite oxidase. SuOX is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. This enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. SuOX deficiency results in neurological abnormalities which are often fatal at an early age. Recombinant human SuOX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sulfite oxidase

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

53.9 kDa (489aa)

Additionnal Information

SuOX, Sulfite oxidase, Sulfite oxidase, EC 1.8.3.1, ATGP3022-10 µg, ATGP3022-20 µg, ATGP3022-50 µg, ATGP3022-100 µg, ATGP3022-250 µg, ATGP3022-500 µg, ATGP3022-1 mg, ATGP3022-10, ATGP3022-20, ATGP3022-50, ATGP3022-100, ATGP3022-250, ATGP3022-500, ATGP3022-1

References & Citations

Rudolph M.J., et al. (2003) Acta Crystallogr. D 59:1183-1191.; ; Kisker C., et al. (1997) Cell 91:973-983.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_000447.2

Uniprot Accession Number

P51687

Species

Human

AA Sequence

ESTHIYT KEEVSSHTSP ETGIWVTLGS EVFDVTEFVD LHPGGPSKLM LAAGGPLEPF WALYAVHNQS HVRELLAQYK IGELNPEDKV APTVETSDPY ADDPVRHPAL KVNSQRPFNA EPPPELLTEN YITPNPIFFT RNHLPVPNLD PDTYRLHVVG APGGQSLSLS LDDLHNFPRY EITVTLQCAG NRRSEMTQVK EVKGLEWRTG AISTARWAGA RLCDVLAQAG HQLCETEAHV CFEGLDSDPT GTAYGASIPL ARAMDPEAEV LLAYEMNGQP LPRDHGFPVR VVVPGVVGAR HVKWLGRVSV QPEESYSHWQ RRDYKGFSPS VDWETVDFDS APSIQELPVQ SAITEPRDGE TVESGEVTIK GYAWSGGGRA VIRVDVSLDG GLTWQVAKLD GEEQRPRKAW AWRLWQLKAP VPAGQKELNI VCKAVDDGYN VQPDTVAPIW NLRGVLSNAW HRVHVYVSP