Recombinant human CD4 protein

CD4 also known as T-cell surface glycoprotein CD4. CD4 functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Recombinant human CD4, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

T-cell surface glycoprotein CD4 isoform 1, T-cell surface glycoprotein CD4 isoform 1, CD4mut

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

44 kDa (396aa)

Additionnal Information

CD4, T-cell surface glycoprotein CD4 isoform 1, T-cell surface glycoprotein CD4 isoform 1, CD4mut, ATGP3020-10 µg, ATGP3020-20 µg, ATGP3020-50 µg, ATGP3020-100 µg, ATGP3020-250 µg, ATGP3020-500 µg, ATGP3020-1 mg, ATGP3020-10, ATGP3020-20, ATGP3020-50, ATGP3020-100, ATGP3020-250, ATGP3020-500, ATGP3020-1

References & Citations

Petris G., et al. (2014) J. Biol. Chem. 289 (1), 1-12; ; Cha Z., et al. (2013) Tumour Biol. 34 (6), 3579-3585;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_000607

Uniprot Accession Number

P01730

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMKKVVL GKKGDTVELT CTASQKKSIQ FHWKNSNQIK ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VEDQKEEVQL LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS VSQLELQDSG TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE KLTGSGELWW QAERASSSKS WITFDLKNKE VSVKRVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLA LEAKTGKLHQ EVNLVVMRAT QLQKNLTCEV WGPTSPKLML SLKLENKEAK VSKREKAVWV LNPEAGMWQC LLSDSGQVLL ESNIKVLPTW STPVQP