Recombinant human Otoraplin/OTOR protein
OTOR also known as Otoraplin, is a member of the melanoma-inhibiting activity gene family. The protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. Recombinant human OTOR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Otoraplin, Otoraplin, FDP, MIAL1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
14.3 kDa (128aa)
Additionnal Information
References & Citations
Robertson N.G., et al. (2000) Genomics 66:242-248.; ; Rendtorff N.D., et al. (2001) Genomics 71:40-52.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_064542
Uniprot Accession Number
Q9NRC9
Species
Human
AA Sequence
LASKK LCADDECVYT ISLASAQEDY NAPDCRFINV KKGQQIYVYS KLVKENGAGE FWAGSVYGDG QDEMGVVGYF PRNLVKEQRV YQEATKEVPT TDIDFFCE
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