Recombinant human CDK1 protein

CDK1 also known as Cyclin-dependent kinase 1 plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. This protein is required in higher cells for entry into S-phase and mitosis. Recombinant human CDK1, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 1 isoform 1, CDC2, CDC28A, P34CDC2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

36.2 kDa (317aa)

Additionnal Information

CDK1, Cyclin-dependent kinase 1 isoform 1, CDC2, CDC28A, P34CDC2, ATGP3012-10 µg, ATGP3012-20 µg, ATGP3012-50 µg, ATGP3012-100 µg, ATGP3012-250 µg, ATGP3012-500 µg, ATGP3012-1 mg, ATGP3012-10, ATGP3012-20, ATGP3012-50, ATGP3012-100, ATGP3012-250, ATGP3012-500, ATGP3012-1

References & Citations

Enserink JM., et al. (2010) Cell Division 5 (11) : 1-41.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_001777

Uniprot Accession Number

P06493

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MEDYTKIEKI GEGTYGVVYK GRHKTTGQVV AMKKIRLESE EEGVPSTAIR EISLLKELRH PNIVSLQDVL MQDSRLYLIF EFLSMDLKKY LDSIPPGQYM DSSLVKSYLY QILQGIVFCH SRRVLHRDLK PQNLLIDDKG TIKLADFGLA RAFGIPIRVY THEVVTLWYR SPEVLLGSAR YSTPVDIWSI GTIFAELATK KPLFHGDSEI DQLFRIFRAL GTPNNEVWPE VESLQDYKNT FPKWKPGSLA SHVKNLDENG LDLLSKMLIY DPAKRISGKM ALNHPYFNDL DNQIKKM