Recombinant human CDK1 protein
CDK1 also known as Cyclin-dependent kinase 1 plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. This protein is required in higher cells for entry into S-phase and mitosis. Recombinant human CDK1, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Cyclin-dependent kinase 1 isoform 1, CDC2, CDC28A, P34CDC2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
36.2 kDa (317aa)
Additionnal Information
References & Citations
Enserink JM., et al. (2010) Cell Division 5 (11) : 1-41.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_001777
Uniprot Accession Number
P06493
Species
Human
AA Sequence
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