Recombinant human KLF4 protein

KLF4 also known as Kruppel-like factor4. KLF4 is a transcription factor which acts as both an activator and repressor. This protein is expressed principally in erythroid tissues and found predominantly in gut. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Recombinant human KLF4 protein, was expressed in E. coli

Product Specifications

Product Name Alternative

Kruppel-like factor 4, EZF, GKLF

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

44.2 kDa (422aa)

Additionnal Information

KLF4, Kruppel-like factor 4, EZF, GKLF, ATGP3009-10 µg, ATGP3009-20 µg, ATGP3009-50 µg, ATGP3009-100 µg, ATGP3009-250 µg, ATGP3009-500 µg, ATGP3009-1 mg, ATGP3009-10, ATGP3009-20, ATGP3009-50, ATGP3009-100, ATGP3009-250, ATGP3009-500, ATGP3009-1

References & Citations

Wei X., et al (2007) . Cancer Res. 67:1853-1858.; ; Zhang P., et al (2010) . J. Biol. Chem. 285:9180-9189.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_004226

Uniprot Accession Number

O43474

Species

Human

AA Sequence

AVS DALLPSFSTF ASGPAGREKT LRQAGAPNNR WREELSHMKR LPPVLPGRPY DLAAATVATD LESGGAGAAC GGSNLAPLPR RETEEFNDLL DLDFILSNSL THPPESVAAT VSSSASASSS SSPSSSGPAS APSTCSFTYP IRAGNDPGVA PGGTGGGLLY GRESAPPPTA PFNLADINDV SPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLSAPGSEYG SPSVISVSKG SPDGSHPVVV APYNGGPPRT CPKIKQEAVS SCTHLGAGPP LSNGHRPAAH DFPLGRQLPS RTTPTLGLEE VLSSRDCHPA LPLPPGFHPH PGPNYPSFLP DQMQPQVPPL HYQELMPPGS CMPEEPKPKR GRRSWPRKRT AT