Recombinant human CLEC-2/CLEC1B protein
CLEC1B also known as C-type lectin domain family 1 member B. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Recombinant human CLEC1B, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
C-type lectin domain family 1 member B, CLEC2, CLEC-2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.1 kDa (198aa)
Additionnal Information
References & Citations
Manne BK., et al. (2013) J. Biol. Chem. 288 (11), 7717-7726; ; Hughes CE., et al. (2013) J. Biol. Chem. 288 (7), 5127-5135
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_057593
Uniprot Accession Number
Q9P126
Species
Human
AA Sequence
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