Recombinant human BDNF protein

BDNF also known as Brain-derived neurotrophic factor. This protein is during development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. Recombinant human BDNF protein, was expressed in E. coli.

Product Specifications

Product Name Alternative

Brain-derived neurotrophic factor isoform a, ANON2, BuLN2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

15.8 kDa (140aa)

Additionnal Information

BDNF, Brain-derived neurotrophic factor isoform a, ANON2, BuLN2, ATGP3000-10 µg, ATGP3000-20 µg, ATGP3000-50 µg, ATGP3000-100 µg, ATGP3000-250 µg, ATGP3000-500 µg, ATGP3000-1 mg, ATGP3000-10, ATGP3000-20, ATGP3000-50, ATGP3000-100, ATGP3000-250, ATGP3000-500, ATGP3000-1

References & Citations

Egan M.F., et al (2003) . Cell 112:257-269.; ; Ribases M., et al (2003) . Mol. Psychiatry 8:745-751.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_001700

Uniprot Accession Number

P23560

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR