Recombinant mouse Annexin A1/ANXA1 protein

Anxa1 also known as Annexin 1 belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximately 35, 000 to 40, 000 and are preferentially located on the cytosolic face of the plasma membrane. Anxa1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Recombinant mouse Anxa1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, phospholipase A2 inhibitory protein, p35, Annexin Ac2-26, ANX1, LPC1

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

41.1 kDa (369aa) confirmed by MALDI-TOF

Additionnal Information

Annexin A1, Annexin A1, Anx-1, Anx-A1, C430014K04Rik, Lpc-1, Lpc1, ATGP2995-10 µg, ATGP2995-20 µg, ATGP2995-50 µg, ATGP2995-100 µg, ATGP2995-250 µg, ATGP2995-500 µg, ATGP2995-1 mg, ATGP2995-10, ATGP2995-20, ATGP2995-50, ATGP2995-100, ATGP2995-250, ATGP2995-500, ATGP2995-1

References & Citations

Wallner BP., et al. (1987) Nature, 320 (6057) : 77-81.

Other References

Lee YJ, et al. Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice. (Biomolecules. 2022) {https://pubmed.ncbi.nlm.nih.gov/35327639/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_034860

Uniprot Accession Number

P10107

Species

Mouse

AA Sequence

MAMVSEF LKQARFLENQ EQEYVQAVKS YKGGPGSAVS PYPSFNVSSD VAALHKAIMV KGVDEATIID ILTKRTNAQR QQIKAAYLQE NGKPLDEVLR KALTGHLEEV VLAMLKTPAQ FDADELRGAM KGLGTDEDTL IEILTTRSNE QIREINRVYR EELKRDLAKD ITSDTSGDFR KALLALAKGD RCQDLSVNQD LADTDARALY EAGERRKGTD VNVFTTILTS RSFPHLRRVF QNYGKYSQHD MNKALDLELK GDIEKCLTTI VKCATSTPAF FAEKLYEAMK GAGTRHKALI RIMVSRSEID MNEIKVFYQK KYGISLCQAI LDETKGDYEK ILVALCGGN