Recombinant human CTGF/CCN2 protein

CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein) . CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. Recombinant human CTGF, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Connective tissue growth factor, CCN2, NOV2, HCS24, IGFBP8

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by BCA assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

37.7 kDa (344aa)

Additionnal Information

CTGF, CCN2, Connective tissue growth factor, CCN2, NOV2, HCS24, IGFBP8, ATGP2994-10 µg, ATGP2994-20 µg, ATGP2994-50 µg, ATGP2994-100 µg, ATGP2994-250 µg, ATGP2994-500 µg, ATGP2994-1 mg, ATGP2994-10, ATGP2994-20, ATGP2994-50, ATGP2994-100, ATGP2994-250, ATGP2994-500, ATGP2994-1

References & Citations

Jun JI., et al. (2011) Nat Rev Drug Discov, 10 (12) : 945-63

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Angiogenesis

NCBI Accession Number

NP_001892

Uniprot Accession Number

P29279

Species

Human

AA Sequence

MQNCSGPCRC PDEPAPRCPA GVSLVLDGCG CCRVCAKQLG ELCTERDPCD PHKGLFCDFG SPANRKIGVC TAKDGAPCIF GGTVYRSGES FQSSCKYQCT CLDGAVGCMP LCSMDVRLPS PDCPFPRRVK LPGKCCEEWV CDEPKDQTVV GPALAAYRLE DTFGPDPTMI RANCLVQTTE WSACSKTCGM GISTRVTNDN ASCRLEKQSR LCMVRPCEAD LEENIKKGKK CIRTPKISKP IKFELSGCTS MKTYRAKFCG VCTDGRCCTP HRTTTLPVEF KCPDGEVMKK NMMFIKTCAC HYNCPGDNDI FESLYYRKMY GDMA