Recombinant human CYP2E1 protein
CYP2E1 also known as Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1. 14. 13. n7), is member of the cytochrome P450 mixed-function oxidase system that involved in the metabolism of xenobiotics in the body. While it is involved in the oxidative metabolism of a small range of substrates (mostly small polar molecules), there are many important drug interactions mediated by CYP2E1. Recombinant human CYP2E1, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Cytochrome P450 2E1, CPE1, CYP2E, P450-J, P450C2E
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
56.2 kDa (488aa)
Additionnal Information
References & Citations
Miller DN., et al. (1965) Ann NY Acad Sci, 119 (3) : 957-973.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_000764.1
Uniprot Accession Number
P05181
Species
Human
AA Sequence
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