Recombinant human CD71/TFRC protein

TFRC also known as transferrin receptor protein 1. TFRC is required for iron delivery from transferring to cells. This protein is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. Recombinant human TFRC protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

TRFR, Transferrin receptor protein 1 isoform 1, Transferrin receptor protein 1, TR, TFRC, TFR-1, TFR1, TFR 1, TFR, T9, p90, IMD46, CD71, CD 71

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

77.7 kDa (696aa)

Additionnal Information

TRFR, Transferrin receptor protein 1 isoform 1, Transferrin receptor protein 1, TR, TFRC, TFR-1, TFR1, TFR 1, TFR, T9, p90, IMD46, CD71, CD 71, ATGP2984-10 µg, ATGP2984-20 µg, ATGP2984-50 µg, ATGP2984-100 µg, ATGP2984-250 µg, ATGP2984-500 µg, ATGP2984-1 mg, ATGP2984-010, ATGP2984-020, ATGP2984-050, ATGP2984-100, ATGP2984-250, ATGP2984-500, ATGP2984-01M

References & Citations

Rothenberger S., et al. (1987) Cell 49:423-431; ; Tosoni D., et al. (2005) Cell 123:875-888

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_001121620

Uniprot Accession Number

P02786

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMCKGVEP KTECERLAGT ESPVREEPGE DFPAARRLYW DDLKRKLSEK LDSTDFTGTI KLLNENSYVP REAGSQKDEN LALYVENQFR EFKLSKVWRD QHFVKIQVKD SAQNSVIIVD KNGRLVYLVE NPGGYVAYSK AATVTGKLVH ANFGTKKDFE DLYTPVNGSI VIVRAGKITF AEKVANAESL NAIGVLIYMD QTKFPIVNAE LSFFGHAHLG TGDPYTPGFP SFNHTQFPPS RSSGLPNIPV QTISRAAAEK LFGNMEGDCP SDWKTDSTCR MVTSESKNVK LTVSNVLKEI KILNIFGVIK GFVEPDHYVV VGAQRDAWGP GAAKSGVGTA LLLKLAQMFS DMVLKDGFQP SRSIIFASWS AGDFGSVGAT EWLEGYLSSL HLKAFTYINL DKAVLGTSNF KVSASPLLYT LIEKTMQNVK HPVTGQFLYQ DSNWASKVEK LTLDNAAFPF LAYSGIPAVS FCFCEDTDYP YLGTTMDTYK ELIERIPELN KVARAAAEVA GQFVIKLTHD VELNLDYERY NSQLLSFVRD LNQYRADIKE MGLSLQWLYS ARGDFFRATS RLTTDFGNAE KTDRFVMKKL NDRVMRVEYH FLSPYVSPKE SPFRHVFWGS GSHTLPALLE NLKLRKQNNG AFNETLFRNQ LALATWTIQG AANALSGDVW DIDNEF