Recombinant human IP6K2 protein

IP6K2 also known as Inositol hexakisphosphate kinase 2, belongs to the inositol IPK family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5) . It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Recombinant human IP6K2, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Inositol hexakisphosphate kinase 2 isoform a, IHPK2, PIuS

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

51.3 kDa (446aa)

Additionnal Information

IP6K2, Inositol hexakisphosphate kinase 2 isoform a, IHPK2, PIuS, ATGP2975-10 µg, ATGP2975-20 µg, ATGP2975-50 µg, ATGP2975-100 µg, ATGP2975-250 µg, ATGP2975-500 µg, ATGP2975-1 mg, ATGP2975-10, ATGP2975-20, ATGP2975-50, ATGP2975-100, ATGP2975-250, ATGP2975-500, ATGP2975-1

References & Citations

Fairfax BP., et al. (2012) Nat. Genet. 44 (5), 502-510

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid In. 20 mM Tris-HCl buffer (pH8.0) containing 10% Glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_057375

Uniprot Accession Number

Q9UHH9

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSPAFRAMDV EPRAKGVLLE PFVHQVGGHS CVLRFNETTL CKPLVPREHQ FYETLPAEMR KFTPQYKGVV SVRFEEDEDR NLCLIAYPLK GDHGIVDIVD NSDCEPKSKL LRWTTNKKHH VLETEKTPKD WVRQHRKEEK MKSHKLEEEF EWLKKSEVLY YTVEKKGNIS SQLKHYNPWS MKCHQQQLQR MKENAKHRNQ YKFILLENLT SRYEVPCVLD LKMGTRQHGD DASEEKAANQ IRKCQQSTSA VIGVRVCGMQ VYQAGSGQLM FMNKYHGRKL SVQGFKEALF QFFHNGRYLR RELLGPVLKK LTELKAVLER QESYRFYSSS LLVIYDGKER PEVVLDSDAE DLEDLSEESA DESAGAYAYK PIGASSVDVR MIDFAHTTCR LYGEDTVVHE GQDAGYIFGL QSLIDIVTEI SEESGE