Recombinant human FOSL2 protein

FOSL2, also known as fos-related antigen 2, is a protein that in humans is encoded by the FOSL2 gene. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JuN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Recombinant FOSL2, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Fos-related antigen 2, FRA2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

37.6 kDa (349aa)

Additionnal Information

FOSL2, Fos-related antigen 2, FRA2, ATGP2968-10 µg, ATGP2968-20 µg, ATGP2968-50 µg, ATGP2968-100 µg, ATGP2968-250 µg, ATGP2968-500 µg, ATGP2968-1 mg, ATGP2968-10, ATGP2968-20, ATGP2968-50, ATGP2968-100, ATGP2968-250, ATGP2968-500, ATGP2968-1

References & Citations

Santalucia T, Christmann M, et al. (2003) . Cardiovasc Res. 59 (3) :639-48.; ; Molven A, Houge G, et al. (1996) . Genomics. 38 (1) :72-5.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_005244.1

Uniprot Accession Number

P15408

Species

Human

AA Sequence

MYQDYPG NFDTSSRGSS GSPAHAESYS SGGGGQQKFR VDMPGSGSAF IPTINAITTS QDLQWMVQPT VITSMSNPYP RSHPYSPLPG LASVPGHMAL PRPGVIKTIG TTVGRRRRDE QLSPEEEEKR RIRRERNKLA AAKCRNRRRE LTEKLQAETE ELEEEKSGLQ KEIAELQKEK EKLEFMLVAH GPVCKISPEE RRSPPAPGLQ PMRSGGGSVG AVVVKQEPLE EDSPSSSSAG LDKAQRSVIK PISIAGGFYG EEPLHTPIVV TSTPAVTPGT SNLVFTYPSV LEQESPASPS ESCSKAHRRS SSSGDQSSDS LNSPTLLAL