Recombinant human CYTIP protein

CYTIP, also known as cytohesin-interacting protein, contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. It modulates the activation of ARF genes by CYTH1. Recombinant CYTIP, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Cytohesin-interacting protein, B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

42.7 kDa (384aa)

Additionnal Information

CYTIP, Cytohesin-interacting protein, B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP, ATGP2967-10 µg, ATGP2967-20 µg, ATGP2967-50 µg, ATGP2967-100 µg, ATGP2967-250 µg, ATGP2967-500 µg, ATGP2967-1 mg, ATGP2967-10, ATGP2967-20, ATGP2967-50, ATGP2967-100, ATGP2967-250, ATGP2967-500, ATGP2967-1

References & Citations

Grabher D, Hofer S, et al. (2013) . PLoS One. 8 (2) :e57538.; ; Vanharanta S, Shu W, et al. (2013) . Nat Med. 19 (1) :50-6.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004279

Uniprot Accession Number

O60759

Species

Human

AA Sequence

MSLQR LLQHSSNGNL ADFCAGPAYS SYSTLTGSLT MDDNRRIQML ADTVATLPRG RKQLALTRSS SLSDFSWSQR KLVTVEKQDN ETFGFEIQSY RPQNQNACSS EMFTLICKIQ EDSPAHCAGL QAGDVLANIN GVSTEGFTYK QVVDLIRSSG NLLTIETLNG TMILKRTELE AKLQVLKQTL KQKWVEYRSL QLQEHRLLHG DAANCPSLEN MDLDELSLFG PLPGPGPALV DRNRLSSESS CKSWLSSMTM DSEDGYQTCV SEDSSRGAFS RQTSTDDECF IPKEGDDFLR RSSSRRNRSI SNTSSGSMSP LWEGNLSSMF GTLPRKSRKG SVRKQLLKFI PGLHRAVEEE ESRF