Recombinant human ACP2 protein
ACP2 also known as Lysosomal acid phosphatase isoform 1. ACP2 is composed of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. it is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Recombinant human ACP2, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Lysosomal acid phosphatase isoform 1, LAP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
42.9 kDa (373aa)
Additionnal Information
References & Citations
Moss DW., et al. (1995) Critical reviews in clinical laboratory sciences , 32 (4) : 431-67
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_001601
Uniprot Accession Number
P11117
Species
Human
AA Sequence
Frequently Asked Questions
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