Recombinant human ACP2 protein

ACP2 also known as Lysosomal acid phosphatase isoform 1. ACP2 is composed of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. it is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Recombinant human ACP2, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Lysosomal acid phosphatase isoform 1, LAP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

42.9 kDa (373aa)

Additionnal Information

ACP2, Lysosomal acid phosphatase isoform 1, LAP, ATGP2959-10 µg, ATGP2959-20 µg, ATGP2959-50 µg, ATGP2959-100 µg, ATGP2959-250 µg, ATGP2959-500 µg, ATGP2959-1 mg, ATGP2959-10, ATGP2959-20, ATGP2959-50, ATGP2959-100, ATGP2959-250, ATGP2959-500, ATGP2959-1

References & Citations

Moss DW., et al. (1995) Critical reviews in clinical laboratory sciences , 32 (4) : 431-67

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_001601

Uniprot Accession Number

P11117

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSRSLRFVT LLYRHGDRSP VKTYPKDPYQ EEEWPQGFGQ LTKEGMLQHW ELGQALRQRY HGFLNTSYHR QEVYVRSTDF DRTLMSAEAN LAGLFPPNGM QRFNPNISWQ PIPVHTVPIT EDRLLKFPLG PCPRYEQLQN ETRQTPEYQN ESSRNAQFLD MVANETGLTD LTLETVWNVY DTLFCEQTHG LRLPPWASPQ TMQRLSRLKD FSFRFLFGIY QQAEKARLQG GVLLAQIRKN LTLMATTSQL PKLLVYSAHD TTLVALQMAL DVYNGEQAPY ASCHIFELYQ EDSGNFSVEM YFRNESDKAP WPLSLPGCPH RCPLQDFLRL TEPVVPKDWQ QECQLASGPA DTE