Recombinant human IL-29/IFNL1 protein

IFNL1 also known as Interferon lambda-1. This protein is cytokine with immunomodulatory activity and may play a role in antiviral immunity. It is ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Recombinant human IFNL1, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Interferon lambda 1, IFN-lambda-1, Cytokine Zcyto21, ZCYTO21, Interleukin-29, IL-29

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

22.7 kDa (206aa)

Additionnal Information

IL29, IFN-lambda1, Interferon lambda-1, IL-29, IL29, ATGP2955-10 µg, ATGP2955-20 µg, ATGP2955-50 µg, ATGP2955-100 µg, ATGP2955-250 µg, ATGP2955-500 µg, ATGP2955-1 mg, ATGP2955-10, ATGP2955-20, ATGP2955-50, ATGP2955-100, ATGP2955-250, ATGP2955-500, ATGP2955-1

References & Citations

Kotenko S.V., et al. (2003) Nat. Immunol, 4:69-77

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_742152

Uniprot Accession Number

Q8IU54

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMGPVPT SKPTTTGKGC HIGRFKSLSP QELASFKKAR DALEESLKLK NWSCSSPVFP GNWDLRLLQV RERPVALEAE LALTLKVLEA AAGPALEDVL DQPLHTLHHI LSQLQACIQP QPTAGPRPRG RLHHWLHRLQ EAPKKESAGC LEASVTFNLF RLLTRDLKYV ADGNLCLRTS THPEST