Recombinant human Kallikrein 13/KLK13 protein

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK13 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. Recombinant human KLK13 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Kallikrein related peptidase 13, Kallikrein-13 Kallikrein-like protein 4, KLK-L4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

31.3 kDa (284aa)

Additionnal Information

Kallikrein13, Kallikrein 13, Kallikrein-13, KLK-L4, KLKL4, KLK L4, ATGP2949-10 µg, ATGP2949-20 µg, ATGP2949-50 µg, ATGP2949-100 µg, ATGP2949-250 µg, ATGP2949-500 µg, ATGP2949-1 mg, ATGP2949-010, ATGP2949-020, ATGP2949-050, ATGP2949-100, ATGP2949-250, ATGP2949-500, ATGP2949-01M

References & Citations

Friedman J.S., et al. (2002) Hum. Mol. Genet. 11:1333-1342

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_056411

Uniprot Accession Number

Q9UKR3

Species

Human

AA Sequence

GGVSQES SKVLNTNGTS GFLPGGYTCF PHSQPWQAAL LVQGRLLCGG VLVHPKWVLT AAHCLKEGLK VYLGKHALGR VEAGEQVREV VHSIPHPEYR RSPTHLNHDH DIMLLELQSP VQLTGYIQTL PLSHNNRLTP GTTCRVSGWG TTTSPQVNYP KTLQCANIQL RSDEECRQVY PGKITDNMLC AGTKEGGKDS CEGDSGGPLV CNRTLYGIVS WGDFPCGQPD RPGVYTRVSR YVLWIRETIR KYETQQQKWL KGPQ