Recombinant human MDL-1/CLEC5A protein

CLE5CA, also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL1), is a C-type lectin. It appears to be a member of a significant myeloid lineage activating pathway. This protein functions as a positive regulator of osteoclastogenesis and regulates inflammatory responses. Recombinant human CLEC5A protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

C-type lectin domain family 5 member A, C-type lectin domain family 5 member A isoform 1, CLEC5A, CLECSF5, MDL-1, MDL1, Macroprhage lectin 2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

20.8 kDa (184aa)

Additionnal Information

CLEC5A, CLECSF5, C-type lectin domain family 5 member A, C-type lectin domain family 5 member A isoform 1, Kidney associated DCDC2 antisense RNA 1, Macroprhage lectin 2, MDL1, MDL-1, RU2, RU2 antisense gene protein, Ru2AS, ATGP2946-10 µg, ATGP2946-20 µg, ATGP2946-50 µg, ATGP2946-100 µg, ATGP2946-250 µg, ATGP2946-500 µg, ATGP2946-1 mg, ATGP2946-010, ATGP2946-020, ATGP2946-050, ATGP2946-100, ATGP2946-250, ATGP2946-500, ATGP2946-01M

References & Citations

Bakker AB. et al. (1999) Proc Natl Acad Sci u S A. 96:9792-9796.; ; Chen ST. et al. (2008) Nature. 453:672-676.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_037384

Uniprot Accession Number

Q9NY25

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSPQIFNKS NDGFTTTRSY GTVSQIFGSS SPSPNGFITT RSYGTVCPKD WEFYQARCFF LSTSESSWNE SRDFCKGKGS TLAIVNTPEK LKFLQDITDA EKYFIGLIYH REEKRWRWIN NSVFNGNVTN QNQNFNCATI GLTKTFDAAS CDISYRRICE KNAK