Recombinant human SCO1 protein

Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. Recombinant human SCO1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein SCO1 homolog mitochondrial, Protein SCO1 homolog, mitochondrial, SCOD1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

20.5 kDa (179aa) confirmed by MALDI-TOF

Additionnal Information

SCO1, Protein SCO1 homolog mitochondrial, Protein SCO1 homolog, mitochondrial, SCOD1, ATGP2928-10 µg, ATGP2928-20 µg, ATGP2928-50 µg, ATGP2928-100 µg, ATGP2928-250 µg, ATGP2928-500 µg, ATGP2928-1 mg, ATGP2928-10, ATGP2928-20, ATGP2928-50, ATGP2928-100, ATGP2928-250, ATGP2928-500, ATGP2928-1

References & Citations

Petruzzella V., et al. (1999) Genomics. 54 (3) : 494-504.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004580

Uniprot Accession Number

O75880

Species

Human

AA Sequence

MGKPLLGGPF SLTTHTGERK TDKDYLGQWL LIYFGFTHCP DVCPEELEKM IQVVDEIDSI TTLPDLTPLF ISIDPERDTK EAIANYVKEF SPKLVGLTGT REEVDQVARA YRVYYSPGPK DEDEDYIVDH TIIMYLIGPD GEFLDYFGQN KRKGEIAASI ATHMRPYRKK SLEHHHHHH