Recombinant human FGFBP1 protein

FGFBP1 is a secreted fibroblast growth factor carrier protein. This protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. It may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. Recombinant human FGFBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fibroblast growth factor-binding protein 1, FGFBP, FGF-BP, FGF-BP1, FGFBP-1, FGF-binding protein 1, 17 kDa heparin-binding growth factor-binding protein, 17 kDa HBGF-binding protein, HBp17

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

26.2 kDa (234aa) confirmed by MALDI-TOF

Additionnal Information

FGF-BP, Fibroblast growth factor-binding protein 1, Fibroblast growth factor-binding protein 1, FGF-BP, FGF-BP1, FGFBP, FGFBP-1, HBP17, ATGP2926-10 µg, ATGP2926-20 µg, ATGP2926-50 µg, ATGP2926-100 µg, ATGP2926-250 µg, ATGP2926-500 µg, ATGP2926-1 mg, ATGP2926-10, ATGP2926-20, ATGP2926-50, ATGP2926-100, ATGP2926-250, ATGP2926-500, ATGP2926-1

References & Citations

Wu D.Q., et al. (1991) J. Biol. Chem. 266:16778-16785.; ; Czubayko F., et al. (1997) Nat. Med. 3:1137-1140.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_005121

Uniprot Accession Number

Q14512

Species

Human

AA Sequence

KKKVKNG LHSKVVSEQK DTLGNTQIKQ KSRPGNKGKF VTKDQANCRW AATEQEEGIS LKVECTQLDH EFSCVFAGNP TSCLKLKDER VYWKQVARNL RSQKDICRYS KTAVKTRVCR KDFPESSLKL VSSTLFGNTK PRKEKTEMSP REHIKGKETT PSSLAVTQTM ATKAPECVED PDMANQRKTA LEFCGETWSS LCTFFLSIVQ DTSC