Recombinant human ELAVL2 protein

ELAVL2 is a neural-specific RNA-binding protein that is known to bind to several 3' uTRs, including its own and also that of FOS and ID. This protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. Recombinant human ELAVL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ELAV-like protein 2, ELAV-like protein 2, HEL-N1, HELN1, HuB

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

40.4 kDa (369aa) confirmed by MALDI-TOF

Additionnal Information

ELAVL2, ELAV-like protein 2, ELAV-like protein 2, HEL-N1, HELN1, HuB, ATGP2925-10 µg, ATGP2925-20 µg, ATGP2925-50 µg, ATGP2925-100 µg, ATGP2925-250 µg, ATGP2925-500 µg, ATGP2925-1 mg, ATGP2925-10, ATGP2925-20, ATGP2925-50, ATGP2925-100, ATGP2925-250, ATGP2925-500, ATGP2925-1

References & Citations

Joeson L., et al. (2007) Mol. Cell. Proteomics 6:798-811.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Scientific Category

Epigenetics and Nuclear Signaling

NCBI Accession Number

NP_001164668

Uniprot Accession Number

Q12926

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMETQLSN GPTCNNTANG PTTINNNCSS PVDSGNTEDS KTNLIVNYLP QNMTQEELKS LFGSIGEIES CKLVRDKITG QSLGYGFVNY IDPKDAEKAI NTLNGLRLQT KTIKVSYARP SSASIRDANL YVSGLPKTMT QKELEQLFSQ YGRIITSRIL VDQVTGISRG VGFIRFDKRI EAEEAIKGLN GQKPPGATEP ITVKFANNPS QKTNQAILSQ LYQSPNRRYP GPLAQQAQRF RFSPMTIDGM TSLAGINIPG HPGTGWCIFV YNLAPDADES ILWQMFGPFG AVTNVKVIRD FNTNKCKGFG FVTMTNYDEA AMAIASLNGY RLGDRVLQVS FKTNKTHKA