Recombinant human CREB3L2 protein

CREB3L2 is a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. This protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human CREB3L2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

CAMP responsive element binding protein 3-like 2, cAMP responsive element binding protein 3-like 2, BBF2H7

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

44 kDa (401aa) confirmed by MALDI-TOF

Additionnal Information

CREB3L2, cAMP responsive element binding protein 3-like 2, cAMP responsive element binding protein 3-like 2, BBF2H7, ATGP2920-10 µg, ATGP2920-20 µg, ATGP2920-50 µg, ATGP2920-100 µg, ATGP2920-250 µg, ATGP2920-500 µg, ATGP2920-1 mg, ATGP2920-10, ATGP2920-20, ATGP2920-50, ATGP2920-100, ATGP2920-250, ATGP2920-500, ATGP2920-1

References & Citations

Kondo S, Saito A, et al. (2007) . Mol Cell Biol. 27 (5) :1716-29.; ; Panagopoulos I, Monsef N, et al. (2010) . Oncol Rep. 24 (5) :1133-9.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 1mM DTT, 0.2M NaCl

Scientific Category

Epigenetics and Nuclear Signaling

NCBI Accession Number

AAI10814

Uniprot Accession Number

Q70SY1

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMEVLESG EQGVLQWDRK LSELSEPGDG EALMYHTHFS ELLDEFSQNV LGQLLNDPFL SEKSVSMEVE PSPTSPAPLI QAEHSYSLCE EPRAQSPFTH ITSDSFNDDE VESEKWYLST DFPSTSIKTE PITDEPPPGL VPSVTLTITA ISTPLEKEEP PLEMNTGVDS SCQTIIPKIK LEPHEVDQFL NFSPKEAPVD HLHLPPTPPS SHGSDSEGSL SPNPRLHPFS LPQTHSPSRA APRAPSALSS SPLLTAPHKL QGSGPLVLTE EEKRTLIAEG YPIPTKLPLS KSEEKALKKI RRKIKNKISA QESRRKKKEY MDSLEKKVES CSTENLELRK KVEVLENTNR TLLQQLQKLQ TLVMGKVSRT CKLAGTQTGT C