Recombinant mouse GDF-15 protein
Growth/differentiation factor 15, also known as GDF15, is a member of the TGF superfamily. It has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. Recombinant mouse GDF15 fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Growth/differentiation factor 15 precursor, Growth/differentiation factor 15 precursor, MIC-1, NAG-1, SBF
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
14.9 kDa (138aa)
Additionnal Information
References & Citations
Zimmers TA, Jin X, et al. (2005) . Shock. 23 (6) :543-8.; ; Hsiao EC, Koniaris LG, et al. (2000) . Mol Cell Biol. 20 (10) :3742-51.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_035949.2
Uniprot Accession Number
Q9Z0J7
Species
Mouse
AA Sequence
SAHAHPR DSCPLGPGRC CHLETVQATL EDLGWSDWVL SPRQLQLSMC VGECPHLYRS ANTHAQIKAR LHGLQPDKVP APCCVPSSYT PVVLMHRTDS GVSLQTYDDL VARGCHCA
Explore Other Products
Browse additional items from our catalog
Recombinant Plasmodium Chabaudi AdoHcyase EC Protein (aa 1-479) (Yeast)
Canine Secretoglobin family 3A member 1 ELISA Kit
Canine Secretoglobin family 3A member 1 ELISA Kit
Canine Secretoglobin family 3A member 1 ELISA Kit
Canine Secretoglobin family 3A member 1 ELISA Kit
