Recombinant human BNIP1 protein

BNIP1 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. This protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, it is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. Recombinant human BNIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Vesicle transport protein SEC20, NIP1, SEC20, TRG-8

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.2 kDa (222aa)

Additionnal Information

BNIP1, Vesicle transport protein SEC20, NIP1, SEC20, TRG-8, ATGP2912-10 µg, ATGP2912-20 µg, ATGP2912-50 µg, ATGP2912-100 µg, ATGP2912-250 µg, ATGP2912-500 µg, ATGP2912-1 mg, ATGP2912-10, ATGP2912-20, ATGP2912-50, ATGP2912-100, ATGP2912-250, ATGP2912-500, ATGP2912-1

References & Citations

Nakajima K., et al. (2004) EMBO J. 23:3216-3226

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Apoptosis

NCBI Accession Number

NP_001196

Uniprot Accession Number

Q12981

Species

Human

AA Sequence

MAAPQDV HVRICNQEIV KFDLEVKALI QDIRDCSGPL SALTELNTKV KEKFQQLRHR IQDLEQLAKE QDKESEKQLL LQEVENHKKQ MLSNQASWRK ANLTCKIAID NLEKAELLQG GDLLRQRKTT KESLAQTSST ITESLMGISR MMAQQVQQSE EAMQSLVTSS RTILDANEEF KSMSGTIQLG RKLITKYNRR EL