Recombinant human BNIP1 protein
BNIP1 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. This protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, it is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. Recombinant human BNIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Vesicle transport protein SEC20, NIP1, SEC20, TRG-8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.2 kDa (222aa)
Additionnal Information
References & Citations
Nakajima K., et al. (2004) EMBO J. 23:3216-3226
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_001196
Uniprot Accession Number
Q12981
Species
Human
AA Sequence
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