Recombinant human RAB3IL protein
Guanine nucleotide exchange factor for Rab-3A isoform 1, also known as RAB3IL, is a 382 amino acid protein that belongs to the SEC2 family. RAB3IL1 is a guanine nucleotide exchange factor (GEF) for Rab3A. RAB3IL1 competes for an interaction with Rab3A and IHPK1 through its coiled coil domain, which does not require IHPK1 kinase activity. Recombinant human RAB3IL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
RAB3A interacting protein like 1, Rabin3-like 1, Guanine nucleotide exchange factor for Rab-3A, GRAB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
45 kDa (405aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Luo H R., et al. (2001) Neuron. 31: 439-451.; ; Rual J F., et al. (2005) Nature. 437: 1173-1178.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_037533
Uniprot Accession Number
Q8TBN0
Species
Human
AA Sequence
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