Recombinant human CD58/LFA-3 protein
CD58 is a member of the immunoglobulin superfamily. This protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane. Alternatively spliced transcript variants have been described. Recombinant human CD58 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
CD58 molecule, CD58 molecule, ag3, LFA-3, LFA3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.8 kDa (210aa)
Additionnal Information
References & Citations
Challa-Malladi, M., et al. (2011) Cancer Cell 20 (6), 728-740; ; Patsopoulos NA, et al. (2011) Ann. Neurol. 70 (6), 897-912;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid In. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001770
Uniprot Accession Number
P19256
Species
Human
AA Sequence
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