Recombinant human VCPKMT protein
VCPKMT is a protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. Recombinant human VCPKMT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Protein-lysine methyltransferase METTL21D, C14orf138, METTL21D, VCP-KMT
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
28.2 kDa (252aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Kernstock S., et al. (2012) Nat. Commun. 3:1038-1038.; ; Cloutier P., et al. (2013) PLoS Genet. 9:E1003210-E1003210.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid In. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Other
NCBI Accession Number
NP_078834
Uniprot Accession Number
Q9H867
Species
Human
AA Sequence
Frequently Asked Questions
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