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Recombinant human DPPA5/ESG1 protein

Developmental pluripotency-associated 5 proteins, also known as DPPA5, is a 116 amino acid protein that localizes to the cytoplasm and contains one KH domain. Expressed in embryonic germ (EG), primordial germ (PG) and embryonic stem (ES) cells, DPPA5 plays an important role in the maintenance of ES cell pluripotency and may be necessary for proper embryogenesis. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Recombinant human DPPA5 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Developmental pluripotency-associated 5 proteins, Developmental pluripotency-associated 5 proteins, ESG1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

15.9 kDa (139aa)

Additionnal Information

DPPA5, ESG1, Developmental pluripotency-associated 5 proteins, Developmental pluripotency-associated 5 proteins, ESG1, ATGP2901-10 µg, ATGP2901-20 µg, ATGP2901-50 µg, ATGP2901-100 µg, ATGP2901-250 µg, ATGP2901-500 µg, ATGP2901-1 mg, ATGP2901-10, ATGP2901-20, ATGP2901-50, ATGP2901-100, ATGP2901-250, ATGP2901-500, ATGP2901-1

References & Citations

Kim S K., et al. (2005) Stem Cells. 23: 458-462.; ; Pirre A., et al. (2007) Genomics. 90: 583-594.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Phosphate buffer (pH 8.0) containing 10% glycerol

Scientific Category

Stem cell

NCBI Accession Number

NP_001020461

Uniprot Accession Number

A6NC42

Species

Human

AA Sequence

MGTLPAR RHIPPWVKVP EDLKDPEVFQ VQTRLLKAIF GPDGSRIPYIEQVSKAMLEL KALESSDLTE VVVYGSYLYK LRTKWMLQSM AEWHRQRQER GMLKLAEAMN ALELGPWMK

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