Recombinant rat VEGFA protein
Vascular endothelial growth factor A isoform 3, also known as VEGFA, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo because the expression pattern of VEGF is consistent with a role in embryonic angiogenesis. Recombinant Rat VEGFA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Vascular endothelial growth factor A isoform 8, Vascular permeability factor, Vegf, VEGF-A, VPF
Expression System
E.coli
Antigen Species
Rat
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.7 kDa (145aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
EI Ghazi F., et al. (2012) Neurobiol. 45: 871-886.; ; Feng J., et al. (2012) Cell Signal. 24: 1116-1125.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_001274039
Uniprot Accession Number
P16612
Species
Rat
AA Sequence
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