Recombinant human TNFRSF3/LTBR protein

LTBR plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. Recombinant human LTBR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Lymphotoxin beta receptor, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, D12S370, TNFCR, TNFR3, TNFR-RP, TNFR2-RP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.6 kDa (224aa) confirmed by MALDI-TOF

Additionnal Information

Lymphotoxin b TNFRSF3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor superfamily member 3, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, ATGP2897-10 µg, ATGP2897-20 µg, ATGP2897-50 µg, ATGP2897-100 µg, ATGP2897-250 µg, ATGP2897-500 µg, ATGP2897-1 mg, ATGP2897-10, ATGP2897-20, ATGP2897-50, ATGP2897-100, ATGP2897-250, ATGP2897-500, ATGP2897-1

References & Citations

Remouchamps, C., et al. (2011) Cytokine Growth Factor Rev. 22 (5-6), 301-310

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT

Scientific Category

Apoptosis

NCBI Accession Number

NP_002333.1

Uniprot Accession Number

P36941

Species

Human

AA Sequence

SQPQAV PPYASENQTC RDQEKEYYEP QHRICCSRCP PGTYVSAKCS RIRDTVCATC AENSYNEHWN YLTICQLCRP CDPVMGLEEI APCTSKRKTQ CRCQPGMFCA AWALECTHCE LLSDCPPGTE AELKDEVGKG NNHCVPCKAG HFQNTSSPSA RCQPHTRCEN QGLVEAAPGT AQSDTTCKNP LEPLPPEMSG TMLM