Recombinant human HDDC2 protein
HDDC2 (HD domain-containing protein 2), also known as hepatitis C virus NS5A-transactivated protein 2, is an enzyme that contains one HD domain and belongs to the HDDC2 family. It is predicted to exhibit phosphohydrolase activity. This protein is suggested to participate in nucleic acid metabolism, signal transduction and possibly other functions in bacteria, archaea and eukaryotes. The HD domain consists of highly conserved residues, specifically histidines or aspartates. Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome have all been associated with this protein. Recombinant human HDDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
HD domain-containing protein 2, HD domain-containing protein 2, C6orf74, CGI-130, dJ167O5.2, NS5ATP2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.8 kDa (227aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Brunner, H.G. et al. (1994) Hum. Mol. Genet. 3:1561-1564.; ; Aravind, L. et al. (1998) Trends Biochem. Sci. 23:469-472.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Other
NCBI Accession Number
NP_057147
Uniprot Accession Number
Q7Z4H3
Species
Human
AA Sequence
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