Recombinant human RPL7A protein

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL7A is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. Recombinant human RPL7A protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

60S ribosomal protein L7a, 60S ribosomal protein L7a, L7A, SuRF3, TRuP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

32.4 kDa (289aa)

Additionnal Information

RPL7A, 60S ribosomal protein L7a, 60S ribosomal protein L7a, L7A, SuRF3, TRuP, ATGP2886-10 µg, ATGP2886-20 µg, ATGP2886-50 µg, ATGP2886-100 µg, ATGP2886-250 µg, ATGP2886-500 µg, ATGP2886-1 mg, ATGP2886-10, ATGP2886-20, ATGP2886-50, ATGP2886-100, ATGP2886-250, ATGP2886-500, ATGP2886-1

References & Citations

Zheng, S.E., et al. (2009) J. Cancer Res. Clin. Oncol. 135 (8), 1025-1031

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_000963

Uniprot Accession Number

P62424

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPKGKKA KGKKVAPAPA VVKKQEAKKV VNPLFEKRPK NFGIGQDIQP KRDLTRFVKW PRYIRLQRQR AILYKRLKVP PAINQFTQAL DRQTATQLLK LAHKYRPETK QEKKQRLLAR AEKKAAGKGD VPTKRPPVLR AGVNTVTTLV ENKKAQLVVI AHDVDPIELV VFLPALCRKM GVPYCIIKGK ARLGRLVHRK TCTTVAFTQV NSEDKGALAK LVEAIRTNYN DRYDEIRRHW GGNVLGPKSV ARIAKLEKAK AKELATKLG