Recombinant human CD37 protein
CD37 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. Recombinant human CD37 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Leukocyte antigen CD37, Leukocyte antigen CD37, GP52-40, TSPAN26
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
17.4 kDa (154aa)
Additionnal Information
References & Citations
Draber P., et al (2011) . Mol. Cell. Biol. 31:4550-4562; ; Classon B.J., et al (1989) . J. Exp. Med. 169:1497-1502;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001765
Uniprot Accession Number
P11049
Species
Human
AA Sequence
RAQLER SLRDVVEKTI QKYGTNPEET AAEESWDYVQ FQLRCCGWHY PQDWFQVLIL RGNGSEAHRV PCSCYNLSAT NDSTILDKVI LPQLSRLGHL ARSRHSADIC AVPAESHIYR EGCAQGLQKW LHNN
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