Recombinant human KLHDC8B protein

KLHDC8B forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in KLHDC8B have been associated with Hodgkin lymphoma. Recombinant human KLHDC8B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Kelch domain-containing protein 8B, FP17659, Kelch domain containing protein 8B, MGC35097

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

40.1 kDa (377aa)

Additionnal Information

KLHDC8B, Kelch domain-containing protein 8B, FP17659, Kelch domain containing protein 8B, MGC35097, ATGP2864-10 µg, ATGP2864-20 µg, ATGP2864-50 µg, ATGP2864-100 µg, ATGP2864-250 µg, ATGP2864-500 µg, ATGP2864-1 mg, ATGP2864-10, ATGP2864-20, ATGP2864-50, ATGP2864-100, ATGP2864-250, ATGP2864-500, ATGP2864-1

References & Citations

Wan D., et al (2004) . Proc. Natl. Acad. Sci. u.S.A. 101:15724-15729; ; Salipante S.J., et al (2009) . Proc. Natl. Acad. Sci. u.S.A. 106:14920-14925;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Other

NCBI Accession Number

NP_775817

Uniprot Accession Number

Q8IXV7

Species

Human

AA Sequence

MSAGGGR AFAWQVFPPM PTCRVYGTVA HQDGHLLVLG GCGRAGLPLD TAETLDMASH TWLALAPLPT ARAGAAAVVL GKQVLVVGGV DEVQSPVAAV EAFLMDEGRW ERRATLPQAA MGVATVERDG MVYALGGMGP DTAPQAQVRV YEPRRDCWLS LPSMPTPCYG ASTFLHGNKI YVLGGRQGKL PVTAFEAFDL EARTWTRHPS LPSRRAFAGC AMAEGSVFSL GGLQQPGPHN FYSRPHFVNT VEMFDLEHGS WTKLPRSLRM RDKRADFVVG SLGGHIVAIG GLGNQPCPLG SVESFSLARR RWEALPAMPT ARCSCSSLQA GPRLFVIGGV AQGPSQAVEA LCLRDGV