Recombinant mouse IL-1 alpha/IL1A protein

IL-1a is produced by activated macrophages, stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. This protein is involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Recombinant mouse IL1a protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Interleukin-1 alpha precursor, Interleukin 1 alpha, IL-1F1, IL-1A, IL-1 alpha

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

20.4 kDa (179aa)

Additionnal Information

Pro-interleukin-1-alpha, Pro interleukin 1 alpha, Preinterleukin 1 alpha, Interleukin-1 alpha precursor, Interleukin 1 alpha, IL1F1, IL-1a, IL1a, IL-1 alpha, IL1 alpha, IL-1 a, IL1 a, IL 1 alpha, IL 1 a, Hematopoietin-1, Hematopoietin1, Hematopoietin 1, ATGP2863-10 µg, ATGP2863-20 µg, ATGP2863-50 µg, ATGP2863-100 µg, ATGP2863-250 µg, ATGP2863-500 µg, ATGP2863-1 mg, ATGP2863-010, ATGP2863-020, ATGP2863-050, ATGP2863-100, ATGP2863-250, ATGP2863-500, ATGP2863-01M

References & Citations

Beuscher H.u., et al (1988) . J. Biol. Chem. 263:4023-4028

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_034684

Uniprot Accession Number

P01582

Species

Mouse

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSSAPYTYQ SDLRYKLMKL VRQKFVMNDS LNQTIYQDVD KHYLSTTWLN DLQQEVKFDM YAYSSGGDDS KYPVTLKISD SQLFVSAQGE DQPVLLKELP ETPKLITGSE TDLIFFWKSI NSKNYFTSAA YPELFIATKE QSRVHLARGL PSMTDFQIS