Recombinant mouse IL-1 alpha/IL1A protein
IL-1a is produced by activated macrophages, stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. This protein is involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Recombinant mouse IL1a protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Interleukin-1 alpha precursor, Interleukin 1 alpha, IL-1F1, IL-1A, IL-1 alpha
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
20.4 kDa (179aa)
Additionnal Information
References & Citations
Beuscher H.u., et al (1988) . J. Biol. Chem. 263:4023-4028
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_034684
Uniprot Accession Number
P01582
Species
Mouse
AA Sequence
Frequently Asked Questions
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