Recombinant human CD300E protein

CMRF35-like molecule 2 precursor, also known as CD300E, is a 205 amino acid single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain and belongs to the CD300 family. Interacting with DAP12, CD300E most likely functions as an activating receptor. CD300E is present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages. Recombinant human CD300E protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

CD300e molecule, CD300 antigen-like family member E, CMRF35-A5, Immune receptor expressed on myeloid cells 2, IREM-2, Polymeric immunoglobulin receptor 2, PIgR-2, PIgR2, Poly-Ig receptor 2, CD300LE, CLM2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

>85% by SDS-PAGE

Molecular Weight

19.9 kDa (179aa)

Additionnal Information

CD300E, CMRF35-like molecule 2 precursor, CD300LE, CLM-2, CLM2, CMRF35-A5, IREM-2, IREM2, PIgR-2, PIgR2, LMIR6, ATGP2862-10 µg, ATGP2862-20 µg, ATGP2862-50 µg, ATGP2862-100 µg, ATGP2862-250 µg, ATGP2862-500 µg, ATGP2862-1 mg, ATGP2862-010, ATGP2862-020, ATGP2862-050, ATGP2862-100, ATGP2862-250, ATGP2862-500, ATGP2862-01M

References & Citations

Clark G J., et al. (2009) Immunobiology. 214: 730-736.; ; Clark G J., et al. (2009) Trends Immunol. 30: 209-217.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea

Scientific Category

Immunology

NCBI Accession Number

NP_852114.2

Uniprot Accession Number

Q496F6

Species

Human

AA Sequence

LKGPGSV TGTAGDSLTV WCQYESMYKG YNKYWCRGQY DTSCESIVET KGEEKVERNG RVSIRDHPEA LAFTVTMQNL NEDDAGSYWC KIQTVWVLDS WSRDPSDLVR VYVSPAITTP RRTTHPATPP IFLVVNPGRN LSTGEVLTQN SGFRLSSPH