Recombinant human ELP4 protein
ELP4 is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. Recombinant human ELP4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Elongator complex protein 4, C11orf19, dJ68P15A.1, PAX6NEB, PAXNEB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
49 kDa (447aa)
Additionnal Information
References & Citations
Strug, L.J., et al. (2009) Eur. J. Hum. Genet. 17 (9), 1171-1181.; ; Miele, A., et al. (2007) J. Cell. Biochem. 102 (1), 136-148.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_061913
Uniprot Accession Number
Q96EB1
Species
Human
AA Sequence
Frequently Asked Questions
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