Recombinant human CSK protein
CSK is a tyrosine-protein kinase CSK that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.. Recombinant human CSK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tyrosine-protein kinase CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, Tyrosine protein kinase CSK
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
53.1 kDa (473aa)
Additionnal Information
References & Citations
Braeuninger A., et al. (1991) Proc. Natl. Acad. Sci. u.S.A. 88:10411-10415
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001120662.1
Uniprot Accession Number
P41240
Species
Human
AA Sequence
Frequently Asked Questions
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