Recombinant human ACTR3 protein

The specific function of ACTR3 has not yet been determined; however, this protein is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. Recombinant human ACTR3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

ARP3 actin-related protein 3, ARP3, Actin-like protein 3, Actin related protein 3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

49.8 kDa (441aa)

Additionnal Information

ACTR3, ARP3 actin-related protein 3, ARP3, Actin-like protein 3, Actin related protein 3, ATGP2835-10 µg, ATGP2835-20 µg, ATGP2835-50 µg, ATGP2835-100 µg, ATGP2835-250 µg, ATGP2835-500 µg, ATGP2835-1 mg, ATGP2835-10, ATGP2835-20, ATGP2835-50, ATGP2835-100, ATGP2835-250, ATGP2835-500, ATGP2835-1

References & Citations

Welch M.D., et al. (1997) Nature. 385:265-269; ; Kim J., et al. (2010) Nature. 464:1048-1051

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_005712

Uniprot Accession Number

P61158

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAGRLPA CVVDCGTGYT KLGYAGNTEP QFIIPSCIAI KESAKVGDQA QRRVMKGVDD LDFFIGDEAI EKPTYATKWP IRHGIVEDWD LMERFMEQVI FKYLRAEPED HYFLLTEPPL NTPENREYTA EIMFESFNVP GLYIAVQAVL ALAASWTSRQ VGERTLTGTV IDSGDGVTHV IPVAEGYVIG SCIKHIPIAG RDITYFIQQL LRDREVGIPP EQSLETAKAV KERYSYVCPD LVKEFNKYDT DGSKWIKQYT GINAISKKEF SIDVGYERFL GPEIFFHPEF ANPDFTQPIS EVVDEVIQNC PIDVRRPLYK NIVLSGGSTM FRDFGRRLQR DLKRTVDARL KLSEELSGGR LKPKPIDVQV ITHHMQRYAV WFGGSMLAST PEFYQVCHTK KDYEEIGPSI CRHNPVFGVM S