Recombinant human DCTN6 protein

DCTN6 contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. Recombinant human DCTN6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Dynactin subunit 6, p27, WS-3, WS3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

23.1 kDa (213aa) confirmed by MALDI-TOF

Additionnal Information

DCTN6, Dynactin subunit 6, p27, WS-3, WS3, ATGP2832-10 µg, ATGP2832-20 µg, ATGP2832-50 µg, ATGP2832-100 µg, ATGP2832-250 µg, ATGP2832-500 µg, ATGP2832-1 mg, ATGP2832-10, ATGP2832-20, ATGP2832-50, ATGP2832-100, ATGP2832-250, ATGP2832-500, ATGP2832-1

References & Citations

Yeh T.Y., et al (2013) EMBO J. 32:1023-1035

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_006562

Uniprot Accession Number

O00399

Species

Human

AA Sequence

MAEKTQK SVKIAPGAVV CVESEIRGDV TIGPRTVIHP KARIIAEAGP IVIGEGNLIE EQALIINAYP DNITPDTEDP EPKPMIIGTN NVFEVGCYSQ AMKMGDNNVI ESKAYVGRNV ILTSGCIIGA CCNLNTFEVI PENTVIYGAD CLRRVQTERP QPQTLQLDFL MKILPNYHHL KKTMKGSSTP VKN