Recombinant human SNAPC1 protein
SNAPC1 is a part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. It binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Also, it recruits TBP and BRF2 to the u6 snRNA TATA box. Recombinant human SNAPC1 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
SnRNA-activating protein complex subunit1, PTFgamma, SNAP43
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
45.4 kDa (391aa)
Additionnal Information
References & Citations
Hinkley C.S., et al. (2003) J. Biol. Chem. 278:18649-18657.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_003073
Uniprot Accession Number
Q16533
Species
Human
AA Sequence
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