Recombinant human SNAPC1 protein

SNAPC1 is a part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. It binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Also, it recruits TBP and BRF2 to the u6 snRNA TATA box. Recombinant human SNAPC1 protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

SnRNA-activating protein complex subunit1, PTFgamma, SNAP43

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

45.4 kDa (391aa)

Additionnal Information

SNAPC1, snRNA-activating protein complex subunit1, PTFgamma, SNAP43, ATGP2817-10 µg, ATGP2817-20 µg, ATGP2817-50 µg, ATGP2817-100 µg, ATGP2817-250 µg, ATGP2817-500 µg, ATGP2817-1 mg, ATGP2817-10, ATGP2817-20, ATGP2817-50, ATGP2817-100, ATGP2817-250, ATGP2817-500, ATGP2817-1

References & Citations

Hinkley C.S., et al. (2003) J. Biol. Chem. 278:18649-18657.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_003073

Uniprot Accession Number

Q16533

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMGTPPGL QTDCEALLSR FQETDSVRFE DFTELWRNMK FGTIFCGRMR NLEKNMFTKE ALALAWRYFL PPYTFQIRVG ALYLLYGLYN TQLCQPKQKI RVALKDWDEV LKFQQDLVNA QHFDAAYIFR KLRLDRAFHF TAMPKLLSYR MKKKIHRAEV TEEFKDPSDR VMKLITSDVL EEMLNVHDHY QNMKHVISVD KSKPDKALSL IKDDFFDNIK NIVLEHQQWH KDRKNPSLKS KTNDGEEKME GNSQETERCE RAESLAKIKS KAFSVVIQAS KSRRHRQVKL DSSDSDSASG QGQVKATRKK EKKERLKPAG RKMSLRNKGN VQNIHKEDKP LSLSMPVITE EEENESLSGT EFTASKKRRK H