Recombinant human IMMP2L protein

IMMP2L is a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. This protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. Recombinant human IMMP2L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Mitochondrial inner membrane protease subunit 2, IMP2, IMP2-LIKE

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

18kDa (161aa) confirmed by MALDI-TOF

Additionnal Information

IMMP2L, mitochondrial inner membrane protease subunit 2, IMP2, IMP2-LIKE, ATGP2800-10 µg, ATGP2800-20 µg, ATGP2800-50 µg, ATGP2800-100 µg, ATGP2800-250 µg, ATGP2800-500 µg, ATGP2800-1 mg, ATGP2800-10, ATGP2800-20, ATGP2800-50, ATGP2800-100, ATGP2800-250, ATGP2800-500, ATGP2800-1

References & Citations

Clarke, R.A., et al. (2012) Transl Psychiatry 2, E158; ; Maestrini E., et al. (2010) Mol. Psychiatry 15 (9), 954-968

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001231535

Uniprot Accession Number

Q96T52

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSRVEGASM QPSLNPGGSQ SSDVVLLNHW KVRNFEVHRG DIVSLVSPKN PEQKIIKRVI ALEGDIVRTI GHKNRYVKVP RGHIWVEGDH HGHSFDSNSF GPVSLGLLHA HATHILWPPE RWQKLESVLP PERLPVQREE E

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