Recombinant human DPY30 protein

As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. This protein may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. Recombinant human DPY30 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein dpy-30 homolog, HDPY-30, Saf19

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

13.6 kDa (122aa) confirmed by MALDI-TOF

Additionnal Information

DPY30, protein dpy-30 homolog, HDPY-30, Saf19, ATGP2797-10 µg, ATGP2797-20 µg, ATGP2797-50 µg, ATGP2797-100 µg, ATGP2797-250 µg, ATGP2797-500 µg, ATGP2797-1 mg, ATGP2797-10, ATGP2797-20, ATGP2797-50, ATGP2797-100, ATGP2797-250, ATGP2797-500, ATGP2797-1